I am really pleased to join the team of Kent Mardal in the mathematics department at the University of Oslo !
Researcher recently observed that the cerebrospinal fluid (CSF) penetrates the brain through perivascular spaces around the vessels and travels through the parenchyma thus having the potential of clearing the brain wastes. However, those observations are not well understood. The driving mechanisms, flow velocities and even transport direction are still controversial.
For the next two years, I will model the CSF transport combining 1D network descriptions of both blood and CSF flow and a 3D poroelastic description of the surrounding tissues. The numerical experiments will help understanding the brain clearance system and its implication in Alzheimer’s disease.